Monday, August 9, 2010

TOPIC DISCUSSION: Hyperkalemia due to cell shifts?

It is always important to make sure that K disorders such as hyper and hypokalemia are not due to cell shifts and Pseudo in nature. Cell shifts usually lead to more of hyperkalemia than hypokalemia. 2% shift in intracellular K to the ECF will result in serum K level of 8meq/L.
What causes Hyperkalemia due to cell shifting
Here is a comprehensive list that is worth looking for ( check out the recent AJKD listed below)

1. Insulin deficiency
2. Acidosis
3. Beta Blockade
4. Hypertonicity
5. Alpha stimulation
6. Rhabdomyolysis
7. Hemolysis
8. Tumor Lysis
9. Periodic Paralysis
10. Digoxin
11. Succinylcholine
12. Rebound after insulin infusion

http://www.ncbi.nlm.nih.gov/pubmed/20493606

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