Paraneoplastic Glomerular Diseases: There are many of them
Membranous most common with solid tumors, MCD with most blood malignancies,
MPGN seen with CLL and blood malignancies, Ig A Nephropathy with lung and solid tumors, FSGS with Lymphoma, Crescentic GN usually with lung cancer and other solid tumors, Immunotactoid with CLL, AA amyloidosis with RCC, Bladder cancers. The list can go on!!
How can one tell that the GN is paraneoplastic? Are there subtle clues?
The 4 ones that have been studied are:
1. Older age of presentation ( average age is 73 with Membranous Nephropathy with malignancy)
2. >20 years of smoking
3. Glomerular leukocyte infiltrate of >8 cells/glomerulus
4. Predominate IgG1 and IgG2
- ► 2018 (27)
- ► 2017 (52)
- ► 2016 (45)
- ► 2015 (63)
- ► 2014 (95)
- ► 2013 (133)
- ► 2012 (201)
- Pregnancy in Chronic Kidney Disease
- CONSULT ROUNDS: Cetuximab therapy and wasting synd...
- TOPIC DISCUSSION: LEAD and the KIDNEY
- Vitamin D- NEJM Review 2011
- IN THE NEWS- TPA vs Heparin- NEJM Study
- Kidney Disease: Racial Disparities from the Inside...
- Dabigatran, and what about its use in Nephrology a...
- The Transplant Web
- TOPIC DISCUSSION: Blood Urea Nitrogen ( BUN)
- Diabetic Nephropathy Video on You tube
- 2011 Guest Lecture Series (Part 1 of 2): Gerald A...
- TOPIC DISCUSSION: Thiazides and Hyponatremia
- IN THE NEWS--> Storytelling and Hypertension
- Fibrosis with Inflammation at One Year Predicts Tr...
- NSLIJ - Innate B Cell in Humans that Protects Agai...
- IN THE NEWS-->AngII and Metabolic Syndrome
- TOPIC DISCUSSION: Magnesium for pre eclampsia?
- IN THE NEWS:- THE BOLDE Study
- TOPIC DISCUSSION: Paraneoplastic Glomerulopathy
- Informing the Debate: Rates of Kidney Transplantat...
- History of Nephrology: The Korean War 1950-3
- TOPIC DISCUSSION: Cryoglobulin Classification Made...
- CLINICAL CASE 31, ANSWER and SUMMARY
- Quiz 9 Answers
- HISTORY LESSON- Scribner Shunt
- IN THE NEWS --> Cytoresistance and the kidney
- PD University = HD university
- Medicine for residents: urinary calcium and renal ...
- Life After Renal Fellowship Survey Results
- Bisphosphonate Therapy in CKD and ESRD patients
- CONSULT ROUNDS: Amyloidosis vs Light Chain Deposit...
- The Study of Heart and Renal Protection — SHARP Tr...
- Can Alcohol Consumption be protective post transpl...
- DID YOU KNOW? Extra renal Podocyte like systems?
- TOPIC DISCUSSION: Low or negative Anion gap!
- ▼ January (35)
- ► 2010 (461)