Cryoglobulinemia can be damaging to the kidney. Type I,II and III can be associated with certain disorders all of which can be leading to kidney disease.
Type I:- Monoclonal IgG or IgM:- Myeloma, MGUS, Waldenstrom's, CLL, Lymphoma( all of these can have renal involvement)
Type II:- Monoclonal IgM + polyclonal IgG:- most common- Hep C infection, CLL, Idiopathic
Type III:- Polyclonal IgG +IgM:- Lymphoproliferative diseases, some chronic infections, SLE or Rheumatoid Arthritis.
Cohen. Eric. Cancer and the Kidney, Second Edition. Oxford Press. 2010.
Saturday, January 15, 2011
TOPIC DISCUSSION: Cryoglobulin Classification Made simple!
Posted by Kenar D Jhaveri( kidney 007) at 7:44 AM
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