Hemoperfusion is the passage of anticoagulated blood through a column containing activated charcoal or resins that helps remove lipid bound and water bound drugs. Drug removal using this form might be superior to hemodialysis. If the drug is water soluble, and has significant metablic complications and rebound properties, hemodialysis might be better. If the drug is lipid soluble like barbiturates, hypnotics, sedatives and digitalis might work better with hemoperfusion.
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