Severe hyponatremia (<120 mEq/L) in hospitalized patients has a high mortality rate. This new study in CJASN 2011 issue online reviews this in a retrospective fashion. Medical records of 53 patients who died after developing Na <120 mEq/L before or after admission and of 32 patients who survived after developing Na <110 mEq/L were reviewed. Mortality rates tended to increase as the Na fell from 134 to 120 mEq/L.
Interestingly, Less than Na of 120 mEq/L, the trend reversed, such that the mortality rate progressively decreased as Na fell. More than two thirds of patients who died after Na <120mEq/L had at least two additional acute severe progressive illnesses, most commonly sepsis and multiorgan failure. Most patients who survived with Na <110 mEq/L had medication-induced hyponatremia. The authors conclude that the nature of underlying illness rather than the severity of hyponatremia best explains mortality associated with hyponatremia. Neurologic complications from hyponatremia are uncommon among patients who die with hyponatremia.
- ► 2019 (42)
- ► 2018 (57)
- ► 2017 (52)
- ► 2016 (45)
- ► 2015 (63)
- ► 2014 (95)
- ► 2013 (133)
- ► 2012 (201)
- TOPIC DISCUSSION: The return of "Spironolactone"
- Match the drugs with the toxicity game!
- CLINICAL CASE and ANSWERS 38
- TOPIC DISCUSSION: Clinical Pearls for electrolytes!
- TOPIC DISCUSSION: Origins of the 1.73m2 in the GFR...
- Prolia or Xgeva, Denosumab and The Renal world!
- Alemtuzumab for Induction- the 2011 update
- TOPIC DISCUSSION: Hibernating Bear's urine?
- CONSULT ROUNDS: Ethylene Glycol Toxicity
- Asian Dialysis Modality Survey by Pediatric Nephro...
- Check out this website
- Tumor Lysis Syndrome
- Medicine for residents: Elevated pulse pressure an...
- TOPIC DISCUSSION: Micro Rnas and Chronic Kidney Di...
- Nephrology Crosswords- Pediatric Nephrology
- NKF 2011 Recap- Rhabdomyolysis as the theme
- Donor Risk Scores?
- CLINICAL CASE 37, ANSWERS AND SUMMARY
- "Brain Drain" in nephrology
- TOPIC DISCUSSION: The Distal Hypoperfusion Ischemi...
- Nephrology Fellow Career Choice Satisfaction Survey
- Dual Live Transplants performed
- Interesting Urine Lytes
- NKF 2011 Live: First Clinical Guidelines on Acute ...
- CLINICAL CASE 36, ANSWERS AND SUMMARY
- IN THE NEWS- Hyponatremia and Mortality( its the u...
- ▼ May (26)
- ► 2010 (461)