A recent study in AJT March 2010 issue evaluated what happens to patients after they get a kidney transplant in terms of their nephrogenic systemic fibrosis disease. They studied 17 patients retrospectively.
Nine of 11 transplanted patients had NSF pre transplant and 2 had post transplant DGF and then NSF.
6 dialysis patients with NSF were also studied. They followed these patients for 35 months for post transplant patients and 9 months for dialysis patients. Baseline GFR for transplant patients were 42ml.min.
NSF only improved in 55% of transplant patients and 50% of non transplanted patients. Of the 6 patients of the 11 total transplanted patients, 4 had partial remission and 2 had complete remission of NSF.
It seems that they summarize that transplant or no transplant, 50% had some remission of NSF. So it doesn't seem that transplantation changed outcomes for their NSF.
This is important as this is the largest study of NSF in transplant patients I found so far. Hopefully a more prospective study might be more helpful. In general, i think we are going to see less and less of this disease as we are avoiding gadolinium based MRIs in many of our CKD and post transplant CKD patients.
- ► 2017 (48)
- ► 2016 (45)
- ► 2015 (63)
- ► 2014 (95)
- ► 2013 (133)
- ► 2012 (201)
- ► 2011 (370)
- CLINICAL CASE 9
- The Online Transplant Center: Post transplant MPGN...
- Post transplant MPGN
- TOPIC DISCUSSION: PCO2, which one is better?
- Image Quiz- Answers
- CONSULT ROUNDS: METHANOL and the EYE?
- CONSULT ROUNDS: ACID BASE
- JOURNAL CLUB: Kidney allograft nephrectomy can imp...
- TOPIC DISCUSSION: Nutrition
- TOPIC DISCUSSION: Drugs and Cyclosporine
- IN THE NEWS- NSF and Kidney Transplantation
- Bowel Transplantations, not enough!
- Horseshoe Kidney
- The Online Transplant Center: New Agents for renal...
- CLINICAL CASE 8
- History of Nephrology: The first randomised contro...
- Common Sense vs. Evidence-based Medicine
- TOPIC DISCUSSION: DIFFERENT TYPES OF PROTEINURIA
- New Agents for renal transplantation
- TOPIC DISCUSSION: Renal Artery Stenosis
- TOPIC DISCUSSION: THE WWW and the NEPHROLOGIST
- IN THE NEWS- Hyperkalemia treatment in trouble
- IN THE NEWS ---> ACUTE KIDNEY INJURY
- CONSULT ROUNDS: SIADH and Escitalopram ( lexapro)...
- CONSULT ROUNDS: Clinical dilemma in Nephrogenic Di...
- CONSULT ROUNDS: Metformin toxicity, Lactic Acidosi...
- CLINICAL CASE 7
- IN THE NEWS- HgA1C for Diabetes Diagnosis. How abo...
- KIDNEY DONORS have Good Long term survival
- TOPIC DISCUSSION: VEGF Nephropathology
- TOPIC DISCUSSION: Post Transplant Collapsing FSGS,...
- Post Transplant Collapsing FSGS: Is it really all ...
- CLINICAL CASE 6
- Topic Discussion: OUCH!! Should Anesthesia Hurt?...
- TOPIC DISCUSSION: Alcohol Poisonings, gaps and osm...
- Belatacept approved by FDA
- Protocol Biopsies in Renal Allograft Recipients
- ▼ March (37)