WHY the eye and not other organs like liver, other small vessels? anyone ever wondered? Even as little as 10ml can destroy the optic nerve.
Methanol is a CNS depressant and can cause same effects as alcohol. It also gets metabolised to formic acid via formaldehyde in a process by an enzyme called alcohol dehydrogenase in the liver.
Formic acid can inhibit mitocondrial cytochrome c oxidase leading to hypoxia and anerobic changes leading to acidosis.
The eye has Vitamin A and needs it for functioning. Apparently Vitamin A is metabolized by alcohol dehydrogenase ( the same enzyme), since there is a place for that enzyme there, its possible that the optic nerve becomes a target for methanol's toxication. and not other organs specifically.