Kidney disease in Rheumatoid Arthritis(RA) is not uncommon. Clinical usually seen with isolated proteinuria, hematuria or both and chronic renal dysfunction as well. Studies have shown that if kidney disease is involved, morbidity and mortality is worse.
1. Immunologic disease:- Non immune complex mediated, immune complex mediated, or pauce immune crescentic GN.
- Immune complex is usually 29% of the diseases, followed by Crescentic GN
- The most common immune complex disease is Membranous GN, Ig A and mesangial GN( usually IgM mediated as RF is IgM)
- Crescentic GN is usually pauce immune ANCA( p ANCA positive), older patients and can be also seen with Anti TNF agents
2. Drug induced:- NSAIDS, Gold, other DMARDS, Anti TNF alpha agents induced disease
- Very important class that can lead to interstitial damage, tubular damage, vascular damage, TMA and GNs.
3. AA Amyloidosis
- very hard to treat. Predictor of mortality in RA.
Tuesday, April 12, 2011
TOPIC DISCUSSION: Rheumatoid Arthritis and the Kidney
Posted by Kenar D Jhaveri( kidney 007) at 10:28 AM
Subscribe to: Post Comments (Atom)
- ► 2022 (18)
- ► 2021 (36)
- ► 2020 (32)
- ► 2019 (42)
- ► 2018 (57)
- ► 2017 (52)
- ► 2016 (45)
- ► 2015 (63)
- ► 2014 (95)
- ► 2013 (133)
- ► 2012 (201)
- Fascinating Wordle in AJT 2011
- NKF 2011 Live Blogging from Nephrology on Demand
- TOPIC DISCUSSION: Vascular Amyloidosis and the Kidney
- NKF 2011 Live Blogging: Integrating the treatment ...
- TOPIC DISCUSSION: TMA ( AJKD tells the tale of 2 d...
- Nephron Animation website
- CONSULT ROUNDS: Renal Involvement in Bardet-Biedl ...
- USA-Nephronpower Wordle( Nephrology Rules)
- Dichotomous Effects of Rapamycin
- TOPIC DISCUSSION: The impact of stopping inhibitor...
- Health News - Research brings new hope of renal re...
- AJP Podcasts
- IN THE NEWS--> Salt sensitive HTN and temperature?
- TOPIC DISCUSSION: Renal Denervation for Treatment ...
- CONSULT ROUNDS: Pre Eclampsia
- Online CME resource( Nephrology)
- Pediatrics Grand rounds continue
- TOPIC DISCUSSION: Hypophosphatemia in Nocturnal he...
- Journal CLUB: Pediatric Nephrology
- IN THE NEWS--> Statins and the Kidney after surgery
- Arteries and Kidney Transplant
- Pancreas Transplantation in the Treatment of Diabetes
- IN THE NEWS -MDR-1 polymorphisms in steroid resist...
- TOPIC DISCUSSIONS: Glomerular Disease following co...
- May 2011 Hofstra University Kidney Walk
- IN THE NEWS:- RENALASE and CKD
- Transplant Tourism and Malignancy
- IN THE NEWS --->Innovative tools in nephrology su...
- TOPIC DISCUSSION: Rheumatoid Arthritis and the Kidney
- Cystic Diseases of the Kidney: A primer
- CLINICAL CASE 35, ANSWERS AND SUMMARY
- Submit Kidney Week 2011 Abstracts
- IVIG - how does it work from the Immunology blog?
- JOURNAL CLUB: CHOICE STUDY
- IN THE NEWS- ANCA in the Elderly
- Medicine for residents: Calcium gluconate in a dig...
- IN THE NEWS--> Detective Nephron's next venture
- Neutropenia from Tacrolimus
- IN THE NEWS-- Serum Bilirubin and chronic dialysis...
- ▼ April (39)
- ► 2010 (461)
Great healthy point you have taken on Rheumatoid Arthritis to discuss here. Thank for your great support on this issue.ReplyDelete