Thursday, July 1, 2010

TOPIC DISCUSSION: captopril and stones?

Did you know that our friend captopril, an ace inhibitor can help treat cysteine stones as well? 
Captopril actually has a sulfhydrly group and captopril-cystein disulfide bond is more soluble than cysteine. The dose suggested is usually 75mg to 150mg/day. It might be a good choice for a patient with HTN and cysteine stones as well.




http://www.ncbi.nlm.nih.gov/pubmed/19582183
http://www.ncbi.nlm.nih.gov/pubmed/8488818
http://www.ncbi.nlm.nih.gov/pubmed/2820331

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