Thursday, September 23, 2010

Infections post transplant

We had a good discussion about infections post transplant yesterday ranging from rare cases of Parvovirus B19 to common bacterial infections
A timeline is important to keep in mind.

<1Month into transplant
Think of the common post surgical fever causes
MRSA, Pneumonias
Wound infection
C.diff
Aspiration
BKV can be seen as early as 2 weeks( depending on net immunosuppression state of the patient)
1-6 months into transplant
BK Nephritis
Adenovirus
CMV, PCP
HCV
MAC
>6 months
Back to normal population infections
But also
Nocardia
Atypical fungi
West nile
JC virus( PML)
CMV can happen here as well
So can BKV

A nice review is listed below from NEJM
http://www.ncbi.nlm.nih.gov/pubmed/18094380

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