A recent article published in the Am J of Nephrology raises an interesting question- does drinking more plain water benefit CKD or renal disease? This was a study of analysis of the NHANES database.
Over 3000 patients reviewed and 13% had CKD and 18% had cardiovascular disease.
CKD turned out to be the highest amongst the lowest plain water drinkers( <2 liters/day) and lowest in the highest water drinkers( >4.5L/day).
The authors suggest a protective effect of plain water intake. Unclear what the mechanism of this might be. Two years ago, the Australians had shown a similar finding. In their study, they showed that increased fluid intake was protective for CKD. Increased urine volume might be protective for progression of CKD. Even the lay press in NYTimes took notice of these findings and had a blog post on this very topic.
What is the mechanism for this? Any thoughts, could this be ADH related? or flow related?
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