Monday, March 12, 2012

Topic Discussion: Renin production

The JGA apparatus and renin production in the special smooth muscle cells of the afferent arteriole.
What are the 3 mechanism by which renin production is increased?

1. The Blood pressure monitor in the baroreceptors that notice the decrease in blood flow.
2. The chemo receptors in the macula densa that check for the Na flow in the distal nephron.
3. The baroreceptors in the carotid sinus report back to the nervous system to activate the sympathetic fibers that then activate b1 adrenergic receptors in the JGA to tell the cells to produce renin( hence beta blockers help in renin mediated hypertension)

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