One group of researchers looked at this question.
They compared effect of 1gm three times a day of AT to placebo on well controlled HTN with CAD.
2 week follow up was done. Ambulatory monitoring of BP was done for 24 hours to see changes and endothelial function tests were also done. N =33. The average BP was higher in AT group with statistical significance b 3/2mmHg. Heart rate also increased by 2 beats/min. The biomarkers of endothelial damage, renin and aldosterone levels were unchanged in both groups.
Interesting but so far - only one study, small group of patients, only in one center. A change of BP doesn't seem that significant. We will have to see what else comes out in the future.
2 week follow up was done. Ambulatory monitoring of BP was done for 24 hours to see changes and endothelial function tests were also done. N =33. The average BP was higher in AT group with statistical significance b 3/2mmHg. Heart rate also increased by 2 beats/min. The biomarkers of endothelial damage, renin and aldosterone levels were unchanged in both groups.
Interesting but so far - only one study, small group of patients, only in one center. A change of BP doesn't seem that significant. We will have to see what else comes out in the future.
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