Friday, December 11, 2009


The COOPERATE study had looked at combination ACE inhibitor and ARB therapy in proteinuric patients with non-diabetic kidney disease. The journal Lancet has retracted the paper after the results of an academic investigation indicating some concern regarding the validitiy and ethical issues with the study. Along with the recent ON-TARGET data, its going to be hard to use a combination of ACE and ARB till we get more data. 

Is some proteinuria really bad for the kidney? Or is the kidney doing the right thing to protect itself? No answers!!

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