We have now established the incidence being around 30-40% in the US.
This figure from an article in JASN summarizes the potential way the SARS-Cov2 might be effecting the kidney
Two recent biopsy series from Columbia and Northwell Nephrology showed the variety of pathology reported in COVID-19
In addition, an autopsy series (specific) to the kidneys showed ATN only. Finally, in KI, a series of anti GBM were reported in UK related to COVID-19
All recent papers added interesting few things to the ongoing literature.
1. ATN is by far the most common presentation for AKI( if not pre renal)- even in transplanted kidney. Pigment nephropathy from myoglobin or hemoglobin is rare. Vitamin C overdose induced oxalate nephropathy is rare.
2. Podocytopathies( MCD and cGN) are the most common glomerular findings
3. Other glomerular diseases are a varied amount( TMA, ANCA, Membranous GN, anti GBM)
4. The virus was not found in the kidney with immunohistochemistry in all 3 studies.
Does the kidney get infected?- time will tell.. data is mixed
Post a Comment