Following the simplified Edelman equation: [Na+] = (Nae + Ke)/TBW, hyponatremia can be originated exclusively from a decrease in total exchangeable body sodium (Nae).
Can you think of clinical scenarios where this might occur and that do not involve patients drinking water or hypotonic fluids ?
What do nephrologists think?
Please comment with your responses:
Helbert Rondon, MD
Assistant Professor of Medicine
University of Pittsburgh School of Medicine