Nephrotic syndrome puts at risk for DVT and Renal vein thrombosis. Data to anti-coagulate is weak and not consistent. A recent paper in Jan 2012 issue of KI shares some interesting information.
1. 1313 patients were evaluated( different diagnosis- membranous, IgA, FSGS)
2. 63 month follow up was noted
3. The risk of venous thromboembolism was highest in Membranous GN followed by FSGS compared to IgA Nephropathy.
4. Gender, cancer, proteinuria and serum albumin were adjusted.
5. So instead of degree of proteinuria - it was associated with a specific disease type such as Membranous GN.
6. Why is that? and if so do we need to give anti coagulation?
take a look at the free KI paper for full review:
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