Topic Discussion: Renin production

The JGA apparatus and renin production in the special smooth muscle cells of the afferent arteriole.
What are the 3 mechanism by which renin production is increased?

1. The Blood pressure monitor in the baroreceptors that notice the decrease in blood flow.
2. The chemo receptors in the macula densa that check for the Na flow in the distal nephron.
3. The baroreceptors in the carotid sinus report back to the nervous system to activate the sympathetic fibers that then activate b1 adrenergic receptors in the JGA to tell the cells to produce renin( hence beta blockers help in renin mediated hypertension)

The Call of Renin!

Authors: Kellie Calderon, MD and Kenar Jhaveri, MD

Using creative writing to teach Nephrology: http://www.ncbi.nlm.nih.gov/pubmed/21671849

Creative Writing to Teach Nephrology

We have designed some interesting tools in teaching renal medicine at our institution. One of them has been creative writing.  Check out the " Call of renin"  It is a creative writing piece that dictates the life of "renin" from "renin's" point of view.

http://www.ncbi.nlm.nih.gov/pubmed/21671849