Hyponatremia from MRAs is a rare phenomenon but we have encountered it clinically. There are times, when we check labs after starting spiron...

AKI has been reported with COVID19 ,electrolyte disorders have been less well described. A recent paper in CKJ describe the full spectrum o...

The above figure summarizes the best data on use of serum copeptin level for diagnosis of diabetes inspidus and primary polydipsia. Cope...

Zytiga ( Abiraterone ) is a hormonal chemotherapy agent used to treat prostate cancer. It selectively and irreversibly inhibits CYP17 (17 ...

A solute diuresis is defined -- urine osmolality >600 mosmol/kg and a total daily osmolar output >1000 mosmol (calculated as the ...

Urinary Na concentration is a very useful urinary test that we use in clinical practice to decide the volume status of the patient. It is ...

As we know that a complication of overcorrection of hyponatremia is central pontine myelinolysis(CPM).  Once it happens, what can be done ...

What leads to hyponatremia in adrenal crisis? Pre renal state due to low cortisol   5 (26%) CRH release l...

The arginine vasopressin gene ( AVP gene ), the arginine vasopressin receptor 2 gene ( AVPR2 ), and the vasopressin-sensitive water channel ...

Hyponatremia- Rule of 6 correction. The Stern Approach Correction and then over correction is the concern especially in two population...

Here is a concept map of hyponatremia created by Dr.  Helbert Rondon from  Division of Nephrology,   University of New Mexico School of Med...

We always struggle to diagnosis this entity in few cases of hyponatremia. Measurement of AVP can prove challenging due to problems of orderi...

Labs on presentation: Na 117, K 1.5, Normal renal function. Exam consistent with volume depletion.  EKG changes consistent with hypokalem...

I urge you all to read the piece from Annals of Internal Medicine by Sagalyn called " A little hyponatremic". A beautifully writte...

CHF and SIADH has clear indications for use of vaptans. What is the data and evidence in cirrhosis associated hyponatremia? 1. No drug has...

The relationship of pain and SIADH is well documented. Severe pain can lead to inappropriate ADH production.  Why is that? Why does pain c...

On a recent reading on Sodium and Water physiology, I realized again and again the following points 1. The best way to identify change in ...

1. Oliguric/anuric individual Urine lytes obtained after foley inserted:- Una 27, UK 24, UCl 27 and U Crt 9 2. Hyponatremic individual Na...

Severe hyponatremia (<120 mEq/L) in hospitalized patients has a high mortality rate. This new study in CJASN 2011 issue online reviews th...

Notes from Dr. RW: Hyponatremia update : "This review from CCJM covers the diagnosis and treatment of both acute and chronic forms as w...