Immune checkpoint inhibitors (ICI) are a novel class of immunotherapy drugs that have vastly improved cancer care for patients. Data on AKI ...

  Use of immunotherapy in the renal transplant patient is challenging. Initial case reports had shown over and over acute rejections. In 20...

Two recent studies from US now describe the use of immunotherapy in ESRD patients. Though both are case studies and series, this is encourag...

This is the summary of the renal effects of ICI therapy on the kidney ( as of Dec 2019). This might change as we learn more and more abou...

Check point inhibitors have been associated with kidney injury. The incidence of check point inhibitor associated renal injury varies w...

A new dawn is breaking in the field of hematologic malignancies, as the first product based on chimeric antigen receptor (CAR) T cell...

Use of immunotherapy such as CTLA-4 and PD-1 inhibitors have been sparingly used in renal transplant patients due to the concern for rej...

Since the 1970s, the transplant literature has been soaring with anti rejection medications. In the last decade, we as nephrologists are sta...

Recently, David Rothstein from Pittsburg gave an amazing grand rounds on B regulatory cells in NYSN in New York. Here are some notes on ...

Antibodies have always been the biggest concern in transplantation. During vascular rejection, there is endothelial cell damage. The apopt...

To test your knowledge of induction agents in kidney transplantation, we invite you to complete the following matching quiz. The answers w...

Immunology is evolving rapidly in the medical field. A recent article of mention is the NEJM Nov 2011 issue that talks about the inducible ...

Post infectious GN usually has been associated with hypocomplementemia.  There are certain situations where the complements can be normal an...

TIM is "T cell immunoglobulin mucin". They are molecules that have shown to play a major role in immune responses. TIM 1,3 and 4 a...

A nice letter from investigators at Stanford published this week in NEJM Oct 2011 issue shows a proof of concept. 12 patients, got a HLA ...

The nobel prize this year in 2011 for Medicine is going to the discovery of the Toll like receptors and dendritic cells. Check out the websi...

TIM-1 is a costimulatory molecule that regulates immune responses by modulating CD4 +   T cell effector differentiation. A recent mice study...

Rituximab might be working in a non B cell mediated manner in FSGS recurrence post transplant. A new study by Fornoni et al showed this in ...

T regulatory cells have now come out and made a splash in the transplant world but also in the immunology and glomerular disease world.  T...

Dendritic cells(DC) are traditional thought to be anti infectious and a link between the innate and the adaptive immune system.  A nice br...