Check point inhibitors have been associated with kidney injury. The incidence of check point inhibitor associated renal injury varies w...

A new dawn is breaking in the field of hematologic malignancies, as the first product based on chimeric antigen receptor (CAR) T cell...

Targeted therapies can lead to a glomerular disease. Previously, two reviews didn’t find any glomerular diseases associated with BRAF inhib...

Novel targeted anti-cancer therapies have resulted in improvement in patient survival compared to standard chemotherapy. Renal toxicities ...

Anti PD-1 Inhibitors and the Kidney This includes two proteins called programmed death-1 (PD-1), which is expressed on the surface of im...

B cell malignancies and the Kidney from kdj200

Ifosfamide induced renal damage comes in 6 flavors. The toxic agent is metabolite chloroacetaldehyde rather than the parent drug to the tub...

Ipilimumab is a human monoclonal antibody that targets T lymphocytes antigen-4 or CTLA-4 and it’s used in clinical practice to treat melan...

Cisplatin is one of the most commonly used chemotherapeutic agents.  In the US, there are more than 2000 ongoing clinical trials investig...

Multiple myeloma is the second most common type of hematologic malignancy.  Carfilzomib is a second-generation epoxyketone proteasome...

Does crizotinib cause AKI? and is it reversible? Crizotinib is a ROS-1 inhibitor and acts on anaplastic lymphoma kinase (ALK) to treat non...

Check out this presentation that I gave on some newer chemo agents and renal disease: 1. Ifosfamide: proximal tubular damage, fanconi synd...

Check out the next KI Nephrology Crosswords on Chemotherapy related renal toxicities.