We know that Type 1 DM is a tough condition to have.  Type 1 DM  is an autoimmune condition where the immune system destroys the insulin-pro...

  A Gut Microbiota – Urinary Tract Infection Connection It is presumed that gut bacteria are the source for urinary tract infection, but is ...

Kidney injury post HSCT is a mystery. While the initial AKI is from multiple causes, the chronic damage we see in the survivors of HSCT i...

Krüppel-Like Factors are now creeping their ways in to the Nephrology world. What are they and why is this important for kidney disease-...

Two published studies in JCI might change how we think the body handles “too much salt” https://www.jci.org/articles/view/88532/version...

The complement system can be attacked to help treat kidney disease. Complement activation contributes to the pathogenesis of acute and chron...

What is CLCF1 and how does it matter to the podocyte? CLCF-1( Cardiotrophin like cytokine factor-1) is  a  member of the interleukin ...

Chronic kidney disease (CKD) is a major global public health problem.   In the US, about 11% of adults have CKD as of 2012, and CKD accou...

Cisplatin is one of the most commonly used chemotherapeutic agents.  In the US, there are more than 2000 ongoing clinical trials investig...

A recent article from the Harvard Medical School scientists in Nature shocked the nephrology and transplantation world . Dr Ott, a CT surg...

Some interesting observations have been made on how immune system can modulate blood pressure. First, Guzik et al  reported that mice d...

A number of investigators have zeroed in on the brain as the culprit organ in hypertension.  I'll highlight a few of them h...

At first thought the skin is an unlikely culprit in hypertension.  However, the skin represents the human body’s ...

WHILE WE HAVE BEEN "NEPHRO-CENTRIC" IN THE ROLE OF THE KIDNEY IN HYPERTENSION, WHAT OTHER ORGANS HAVE EMERGED AS POTENTIAL CONTR...

FSGS has been the most researched glomerular disease from a basic science perspective. A recent urge in studying micro RNAs has led to so...

An interesting concept in science is biomimicry. It is the science that takes inspiration from unique designs and processes in nature to h...

Epigenetics refers to a heritable change genetic code that is mediated by a mechanism specifically not due to alterations in the primary n...

A recent review of the pathophysiology of light chain damage in the kidney suggests some novel findings. 1. Apoptosis is a feature of e...

Recently, a study from Singapore published in National Geographic confirmed that turtles urinate via their mouth. Turtles put their head in...

A recent editorial observational piece in JASN Oct 2012 discusses a downward trend in decline of basic science publication in high index jo...