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Monday, January 7, 2013

ESRD and Solid tumors


There is some data that certain cancers have a higher rate in ESRD patients. The largest series that was studied was a cohort of 831,804 patients. 

The highest risks are observed in
Kidney Cancer
Bladder Cancer
Thyroid Cancer
and other endocrine cancers.

Suggested mechanisms: Viral etiology from underlying immunosuppressed state as being ESRD. 
Acquired cystic disease perhaps leads to the increased risk of renal cancer
Loss of renal function or having kidney disease was also proposed as a mechanism( inflammation?)

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