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Friday, November 18, 2011

Complement Component Quiz


Match the following complement components with their function in the complement cascade

C5a
Membrane attack complex

DAF
Initiates the alternative complement pathway

C5b-9
Initiates the classical complement pathway

Factor H
Byproduct of the classical complement pathway

C5
Potent inflammatory mediator

C1q
Membrane bound complement regulatory protein 

C4d
Blockade of this complement component is the treatment for PNF

C3b
Deficiency results in atypical HUS



Good Luck
Answers provided in 1 week

Questions by Dr. Vinay Nair
Mt Sinai, Transplant Division
New York, USA

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