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Friday, November 25, 2011

Complement Component Quiz Answers


Question:



Match the following complement components with their function in the complement cascade

C5a
Membrane attack complex

DAF
Initiates the alternative complement pathway

C5b-9
Initiates the classical complement pathway

Factor H
Byproduct of the classical complement pathway

C5
Potent inflammatory mediator

C1q
Membrane bound complement regulatory protein 

C4d
Blockade of this complement component is the treatment for PNF

C3b
Deficiency results in atypical HUS

Answers:
C5a – Potent inflammatory mediator
DAF (decay accelerating factor) – membrane bound complement regulatory protein
C5b-9 – membrane attack complex (MAC)
Factor H – Deficiency results in atypical HUS (hemolytic uremic syndrome)
C5 - Blockade of this complement component is the treatment for PNF (paroxysmal nocturnal hematuria)
C1q – Initiates the classical complement pathway
C4d - Byproduct of the classical complement pathway
C3b - Initiates the alternative complement pathway

Post by
Vinay Nair 

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