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Monday, February 14, 2011

TOPIC DISCUSSION: Pseudohyperphosphatemia

What are the causes of spurious hyperphosphatemia?
1. Paraproteinemia
2. Hyper builirubinemia
3. Hyperlipidemia
4. Liposomal Amp B preparation
5. Blood sample contamination with tpa or heparin
6. Thrombocythemia

Lot of these errors are due to the type of measurement used in labs- especially the colorimetric assay

A nice case has been discussed in AJKD of a MGUS with pseudohyperphosphatemia.
http://www.ncbi.nlm.nih.gov/pubmed/20951488

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