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Wednesday, August 25, 2010

IN THE NEWS- Hyperkalemia review

 The most recent AJKD 2010 issue has a more physiologic approach to diagnosis of hyperkalemia. The picture on the left from the AJKD article is a must look at! It says a thousand words. When we think of causes of hyperkalemia( not pseudohyperkalemia), if we start from the top with RENIN production to its effect on ANG 1 and then ANG II and Aldosterone to the effects on the principal cell, you won't miss a cause.
Either one of these pathways can be altered leading to hyperkalemia!

References:
http://www.ncbi.nlm.nih.gov/pubmed/20493606
http://www.ncbi.nlm.nih.gov/pubmed/20570423


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