tag:blogger.com,1999:blog-5872673930112727345.post8303371942843821459..comments2024-03-29T03:49:52.282-04:00Comments on Nephron Power: Dabigatran, and what about its use in Nephrology and Transplantation?Kenar D Jhaveri( kidney 007)http://www.blogger.com/profile/08654527832183917798noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-5872673930112727345.post-90157171781357008202012-02-10T19:16:37.820-05:002012-02-10T19:16:37.820-05:00What did you find in the biopsy?What did you find in the biopsy?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5872673930112727345.post-26389606704644475742011-11-08T08:58:54.130-05:002011-11-08T08:58:54.130-05:00I have had a bad experience with this drug in an e...I have had a bad experience with this drug in an elderly renal transplant patient. She was admitted to hospital with acute renal failure and had been on the drug for atrial fib. It took 7 days of daily dialysis before we could biopsy the graft.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5872673930112727345.post-41349938212272707072011-01-28T15:52:02.135-05:002011-01-28T15:52:02.135-05:00I found this information re use in renal impairmen...I found this information re use in renal impairment.( from Uptodate.com based on RE-LY trial and others)<br />US labelling:<br />If Crcl >30: no dose adjustments needed<br />Clcr 15-30 mL/minute: 75 mg twice daily; Note: Patients with Clcr <30 mL/minute were excluded from the RE-LY trial <br />Clcr <15 mL/minute or hemodialysis dependent: No recommendation provided due to insufficient evidence; Note: Hemodialysis removes ~60% over 2-3 hoursKenar D Jhaveri( kidney 007)https://www.blogger.com/profile/08654527832183917798noreply@blogger.com