tag:blogger.com,1999:blog-5872673930112727345.post6660227019127066327..comments2024-03-28T05:54:38.356-04:00Comments on Nephron Power: IN THE NEWS:ACR Lupus Nephritis GuidelinesKenar D Jhaveri( kidney 007)http://www.blogger.com/profile/08654527832183917798noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-5872673930112727345.post-34609327674545069302012-05-12T00:43:40.327-04:002012-05-12T00:43:40.327-04:00The ACR recommendeds to use induction with rituxim...The ACR recommendeds to use induction with rituximab for patients who do not respond to induction and if this fails then to use calcineurin inhibitors. Also, I would add that the ACR recommend to use induction with MMF instead of CYC in African Americans and Hispanics.Dr. Helbert Rondonhttps://www.blogger.com/profile/04527191513403619201noreply@blogger.comtag:blogger.com,1999:blog-5872673930112727345.post-29923609116137036132012-05-09T13:23:11.715-04:002012-05-09T13:23:11.715-04:00There is mention of cyclosporine and tacrolimus in...There is mention of cyclosporine and tacrolimus in the section under " Failing conventional therapy". In a recent prospective trial, tacrolimus was equivalent to high-dose IV CYC in inducing complete and partial remissions. In another 4-year–long prospective trial, cyclosporine was similar to AZA in preventing renal flares in patients receiving maintenance therapy. So there is some data but under the task force guidelines, didn't make it to mainstay therapy.Kenar D Jhaveri( kidney 007)https://www.blogger.com/profile/08654527832183917798noreply@blogger.comtag:blogger.com,1999:blog-5872673930112727345.post-35687105013309978802012-05-09T13:15:27.433-04:002012-05-09T13:15:27.433-04:00I don't see any place for Cyclosporine AI don't see any place for Cyclosporine AVincenzo Montinaro, MDnoreply@blogger.com