tag:blogger.com,1999:blog-5872673930112727345.post4009071524742774535..comments2024-03-28T05:54:38.356-04:00Comments on Nephron Power: TOPIC DISCUSSION: Tamm Horsfall MucoproteinKenar D Jhaveri( kidney 007)http://www.blogger.com/profile/08654527832183917798noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-5872673930112727345.post-68953864769524653382010-02-16T17:29:27.624-05:002010-02-16T17:29:27.624-05:00Common variants in the region of the UMOD gene, wh...Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein) have been associated with chronic kidney disease (CKD) and estimated GFR (eGFR) has been reviewed recently in JASN 2010 Feb issue. They show that urinary uromodulin levels predict incident CKD, in a prospective, case-control study of ten years duration. These findings were then externally replicated. They showed that elevated uromodulin concentrations precede the onset of CKD and associate with a common polymorphism in the UMOD region.Kenar D Jhaveri( kidney 007)https://www.blogger.com/profile/08654527832183917798noreply@blogger.comtag:blogger.com,1999:blog-5872673930112727345.post-38401026775870223372010-02-16T17:28:03.327-05:002010-02-16T17:28:03.327-05:00This comment has been removed by the author.Kenar D Jhaveri( kidney 007)https://www.blogger.com/profile/08654527832183917798noreply@blogger.com