Thursday, September 20, 2018

Topic Discussion: Hormonal levels with various RAAS blockade medications

Class of RAAS agent
Renin level
Plasma renin activity
Ang II level
Aldosterone level
Renin inhibitor
Elevated
Low
Low
Low
ACEI inhibitor*
Elevated
Elevated
Low
Low
ARB*
Elevated
Elevated
Elevated
Low
Aldo receptor blocker
Elevated
Elevated
Elevated
Elevated

* after being on ACEI/ARB for long periods, due to aldosterone breakthrough, aldosterone levels could be high in some cases.

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